The present invention provides a cost-effective, industrially feasible
process for the manufacture of crystalline Carvedilol Form-II using novel
Carvedilol salts comprising a step of reacting 4-(2,3-epoxy
propoxy)carbazole (II) with 2-(2-methoxy phenoxy)ethyl amine (III)
followed by acidification with mineral acid in presence of an organic
solvent to yield acid addition salts, treatment of the said salts with
base(s) in presence of organic solvent(s), water and isolation from the
organic solvent(s) followed by crystallization from ethyl acetate.