A cyclohexane derivative having the function of reducing a blood sugar
level and having preferable properties required of medicines, such as
long-lasting drug activity, metabolic stability, and safety; and a
medicinal composition for use in the prevention or treatment of diseases
attributable to hyperglycemia, such as diabetes, e.g., insulin dependent
diabetes mellitus (type 1 diabetes) or noninsulin-dependent diabetes
mellitus (type 2 diabetes), complications of diabetes, and obesity. The
derivative is a compound represented by the formula (I):
(wherein A is --O--, --CH.sub.2--, or --NH--; n is an integer selected
between 0 and 1; R.sup.6 and R.sup.7 each independently is hydrogen or
C.sub.1-6 alkyl; m is an integer selected among 1-3; Q is selected among
the following formulae Q.sup.1 to Q.sup.5;
Ar.sup.1 is optionally substituted arylene or optionally substituted
heteroarylene, provided that the heteroarylene may be bonded to an
aromatic carbocycle or aromatic heterocycle to form a fused ring; and
Ar.sup.2 is optionally substituted aryl or optionally substituted
heteroaryl), a prodrug of the compound, or a pharmaceutically acceptable
salt of either. Also provided are a medicine, a medicinal composition, or
the like each containing the compound.