Disclosed is a system and method for imaging strain of tissue, such as the
heart, in a quantitative manner. The present invention provides images of
strain, which corresponds to heart function, by tagging a tissue region
of interest, and acquiring multiple images by tuning an MRI RF receiver
to frequencies above and below the tagging frequency. Depending on the
tagging spatial frequency, and the spread between the high- and
low-tuning frequencies, linear measurements of strain may be made on a
pixel by pixel basis. By selectively tagging the tissue of interest by
use of selective excitation, images may be acquired sufficiently fast to
provide anatomical and functional imagery within a single heartbeat. By
acquiring additional images, dead tissue may be differentiated from
contracting tissue as well as blood.