A method and apparatus for measurement reporting and event-triggered periodic measurement reporting in an evolved universal terrestrial radio access network (E-UTRAN) are disclosed. A wireless transmit/receive unit (WTRU) monitors cell-specific reference signals from a serving cell and neighbor cells to detect a reporting event defined for the E-UTRAN. Once a reporting event is detected, the WTRU sends a measurement report to the network. The measurement quantity may be a reference signal received quality (RSRQ). After detection of the reporting event, the WTRU may send event-triggered measurement reports periodically. The WTRU may send a scheduling request to the network for the event-triggered periodic measurement reports. The WTRU may send a termination indication if the event-triggered periodic measurement reports are terminated before a configured number of times. The WTRU may send an extension request if a specified number of periodic reporting has been sent but more reports still need to be sent.