Provided herein are substituted pyrrolopyridine heterocycles and
substituted pyrazolopyridine heterocycles, pharmaceutical compositions
comprising said heterocycles and methods of using said heterocycles in
the treatment of disease. The heterocycles disclosed herein function as
kinase modulators and have utility in the treatment of diseases such as
cancer, allergy, asthma, inflammation, obstructive airway disease,
autoimmune diseases, metabolic disease, infection, CNS disease, brain
tumor, obesity, asthma, hematological disorder, degenerative neural
disease, cardiovascular disease, or disease associated with angiogenesis,
neovascularization, or vasculogenesis.