This invention is related to novel aminoalkyl- and amidoalkyl-benzopyran
derivatives of the following general formula (I)
##STR00001## wherein: the group
##STR00002## is a substituent in position 6 or 7 wherein: R is an
aromatic mono- or bi-cyclic carbocyclic ring or a mono- or bi-cyclic
heterocyclic ring radical, said rings being optionally substituted by one
or two substituents selected from (C.sub.1-C.sub.5) straight or branched
alkyl, (C.sub.1-C.sub.5) straight or branched alkoxy, hydroxy, halogen
and trifluoromethyl; m is zero or an integer from 1 to 3; n, p, R.sub.1
and R.sub.2 are as herein indicated and R.sub.3 and R.sub.4 are both
hydrogen or taken together represent an oxygen atom, and the
pharmaceutically acceptable salts thereof.
The compounds that are active as selective and reversible MAO-B inhibitors
in vitro and in vivo, are useful as medicaments for the prevention and
the treatment of CNS degenerative disorders.