This invention describes novel protein kinase inhibitors of formula VII:
##STR00001## wherein G is Ring C or Ring D; Ring C is selected from a
phenyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or
1,2,4-triazinyl ring, wherein said Ring C has one or two ortho
substituents independently selected from --R.sup.1; Ring D is a 5-7
membered monocyclic ring or 8-10 membered bicyclic ring selected from
aryl, heteroaryl, heterocyclyl or carbocyclyl; R.sup.y is T-R.sup.3''; T
is a valence bond or a C.sub.1-4 alkylidene chain; R.sup.3'' is an
optionally substituted group selected from C.sub.1-6 aliphatic,
C.sub.3-10 carbocyclyl, C.sub.6-10 aryl, a heteroaryl ring having 5-10
ring atoms, or a heterocyclyl ring having 5-10 ring atoms; and R.sup.1,
R.sup.2, and R.sup.2' are as described in the specification. The protein
kinase are useful for treating diseases such as cancer, diabetes and
Alzheimer's disease.