A cationic graft-copolymer for a non-viral gene delivery vector comprising
a unit derived from a cationic derivative of a water-soluble linear
polymers having a hydroxyl groups, namely, a cationic polysaccharide of
the following formula (1) [C6H7O2(OH)3-a (OX)a]x H2O (1) and the cationic
derivative of polyvinylalcohol of the following formula (2) or the
cationic derivative of the partial hydrolyzed polyvinylalcohol of the
following formula (3) [CH2 CH(OH)1-b (OX)b]n (2) [CH2CH(OH)1-b-c (OX)b
(OAc)c]n (3) and a unit derived from a polymerizable olefin compound of
the following formula (4) R4R6.parallel.-C--C--(4).parallel.R5 R7(a, x,
b, n, c, Ac, X, R4, R5, R6, and R7 are defined in claim 1-6); a process
for preparing the same and a transfection reagent made therefrom.
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