It is intended to provide a method for evaluating a compound which
regulates eating or body weight characterized by comprising the steps of
introducing a BARLP gene and preparing a cell expressing BARLP; bringing
a test compound into contact with the cell; and detecting a specific
binding of the test compound to the BARLP and a method for evaluating a
compound further comprising the step of evaluating a test compound using
a nonhuman genetically-engineered animal in which the BARLP gene is
inactivated. According to this invention, knowledge about a relationship
between BARLP and biological functions is obtained and a method for
evaluating a compound targeting BARLP and a BARLP ligand obtained by the
evaluation can be provided.