A system performs program and commercial response monitoring using neuro-response data such as central nervous system, autonomic nervous system, and effector data. Multiple subjects in multiple markets are exposed to programming and commercials and neuro-response data is collected using mechanisms such as Electroencephalography (EEG), Galvanic Skin Response (GSR), Electrocardiograms (EKG), Electrooculography (EOG), eye tracking, and facial emotion encoding. Data collected is provided for response integration to measure and track multi-market program and commercial response to stimulus materials.