In another aspect, the present invention relates to a method for NMR measurements of an arbitrarily shaped region of interest of a living subject. In one embodiment, the method comprises the steps of applying a broad bandwidth of RF pulses to the arbitrarily shaped region of interest to obtain a corresponding spectrum, wherein substantially entire range of chemical shifts in the spectrum is excited from the arbitrarily shaped region of interest, interleaving a plurality of radial k-lines in radial k-space per excitation with non-selective refocusing pulses and obtaining spatial localization for the spectrum of the arbitrarily shaped region of interest.