The present invention relates to an ameliorant for improving the movement
of the digestive tract comprising, as an active ingredient,
4-amino-5-chloro-2-methoxy-N-[(2S,4S)-2-hydroxymethyl-4-pyrrolidinyl]benz-
amide or an acid addition salt thereof which is a metabolite of
4-amino-5-chloro-2-methoxy-N-[(2S,4S)-1-ethyl-2-hydroxymethyl-4-pyrrolidi-
nyl]benzamide or an acid addition salt thereof, having high biding
affinity for a serotonin receptor 4 (5HT.sub.4) and causing no arteritis
and thrombus formation; a medicinal composition for improving the
movement of the digestive tract comprising the said ameliorant and a
pharmaceutically acceptable carrier; and a treating method for promoting
the movement of the digestive tract, which comprises using the said
medicinal composition for improving the movement of the digestive tract.