An implant composition having controlled resorption rate in vivo for
stimulating bone growth, a method of making the implant composition, and
a kit of implant materials are disclosed. The implant composition
includes a calcium sulfate compound, polymer containing particles, and a
setting agent. The polymer is one or more poly(desaminotyrosyl-tyrosine
alkyl ester carbonate). Upon setting, the calcium sulfate compound forms
a matrix and the polymer containing particles settled within the matrix.
The resorption rate of the implant composition in vivo can be controlled
of between eight and twenty-four weeks, which substantially matches the
rate of bone growth. The implant composition of the present invention can
be used for the repair, augmentation, and other treatment of bone.