Disclosed is a process for the production of botanic extracts containing
at least 15% by weight of oligomeric proanthocyanidins of the OPC A2
type, comprising: (a) subjecting shells of the fruit of Litchi sinensis
to extraction with lower, optionally aqueous aliphatic alcohols; (b)
subjecting the extracts to chromatographic separation; (c) subjecting the
OPC A2-rich fraction obtained in the chromatography step to a
liquid/liquid extraction; and (d) removing the resulting organic phase.