The present invention relates to the delivery of antihistamines through an
inhalation route. Specifically, it relates to aerosols containing
antihistamines that are used in inhalation therapy. In a method aspect of
the present invention, an antihistamine is delivered to a patient through
an inhalation route. The method comprises: a) heating a composition,
wherein the composition comprises an antihistamine, to form a vapor; and,
b) allowing the vapor to cool, thereby forming a condensation aerosol
comprising particles with less than 5% antihistamine drug degradation
products. In a kit aspect of the present invention, a kit for delivering
an antihistamine through an inhalation route is provided which comprises:
a) a thin coating of an antihistamine drug composition and b) a device
for dispensing said thin coating as a condensation aerosol.