The invention relates to an amphiphilic-BMP polymer complex which is
physically and chemically stable and soluble in water, characterised in
that: the amphiphilic polymers comprise a hydrophilic polysaccharide
skeleton functionalised with hydrophobic substituents and hydrophilic
groups the BMP is selected from the group of therapeutically active BMPs
(Bone morphogenetic Proteins), the polymer/BMP mass ratio is lower than
or equal to 700.
The invention also relates to the process for preparing the
amphiphilic-BMP polymer complex in an aqueous medium and in the absence
of organic solvents likely to denature the protein.
The invention also relates to therapeutic compositions of an
amphiphilic-BMP polymer complex according to the invention.