Tissue Factor (natural or recombinant truncated) can be incorporated into
stable, soluble nanoscale particles so that activity is maintained. These
particles can be used as a reagent in prothrombin clotting time assays or
they can be used in therapeutic compositions for use in humans or
animals. Therapeutic settings can include supplementation in the case of
a genetic deficiency, uncontrolled bleeding, surgical incisions or
seepage, thrombocytopenia, soft tissue trauma or other trauma, to effect
tumor regression or to inhibit tumor growth.