The present invention provides a method of purifying RNA, including
contacting a solid support with an acidic solution having a
RNA-containing sample and a kosmotropic salt having a concentration of
less than 1M, thereby binding the RNA to the solid support. According to
the present invention, RNA is purified efficiently due to high RNA yield
and low contamination by DNA. The present invention is particularly
effective in purifying RNAs of 200 nucleotides or less.