A remote control device for wirelessly controlling a second device is disclosed that allows the user to remotely control the second device using spoken commands. The remote control device is preferably dimensioned to be useful as a handheld device. The remote control device includes one or more microphones into which the user can speak a command. The remote control device also includes a transmitter, for example a radio frequency transmitter and/or an optical transmitter, for transmitting a signal to the second device based on the user's spoken command.