In accordance with embodiments, there are provided mechanisms and methods for suspending work by a resource adapter. These mechanisms and methods for suspending work by a resource adapter can enable embodiments to provide the capability to start and stop work performed by a resource adapter to connector architectures. The ability of embodiments to provide the capability to start and stop work performed by a resource adapter can enable users of Connector Architectures to quiesce an adapter's inbound/outbound or work sections. Such capability can enable an adapter embodiment to complete in-flight transactions but not accept new inbound transactions until a request to resume operation is received. Resource adapters may be quiesced during a versioning or change out process or other maintenance processes for example.