A memory system is disclosed. The memory system includes a memory controller coupled to one or more memory modules, at least one of the memory modules including a buffer. The memory controller is configured to convey a command to at least one of the memory modules in response to detecting that no memory requests addressed to the at least one of the memory modules have been received during a specified window of time. In response to the command, the buffer of the at least one of the memory modules is configured to enter a reduced power state. The specified window of time may be either a specified number of memory refresh intervals or buffer sync intervals. The memory controller maintains a count of memory refresh or buffer sync intervals.