The present invention relates to in vitro cultured skin tissue, and in particular to cultured skin tissue comprising exogenous genes encoding angiogenic growth factors. In some embodiments, the keratinocytes express exogenous angiopoietin-1 or a member of the VEGF family, preferably VEGF-A. In particularly preferred embodiments, the keratinocytes are incorporated into cultured skin tissue.

 
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> Nucleic acids encoding a novel influenza virus non-structural protein (NS1)-binding host factor designated NS1I-1

> Immunostimulatory oligonucleotide multimers
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