Activation of electrogenic pump molecules can be realized by a dynamic
entrainment procedure which includes two steps: synchronization of
individual pump molecules to work at the same pumping pace, and gradual
modulation of the synchronization frequency. We studied synchronization
of the Na/K pump molecules in a physiological running mode by applying
the concept of an electronic synchrotron to the biological system. Both
theoretical analysis and experimental results showed that individual Na/K
pump molecules can be synchronized by a well designed oscillating
electric field. The synchronized pump currents show separated inward and
outward pump currents and a magnitude ratio of 3:2 reflecting
stoichiometric number of the pump molecules.