A nutritional supplement composition for humans, animals, and plants is provided which comprises sea water elements and minerals in substantially the same proportion as in natural sea water or sea water and a caloric nutrient source. Preferably, the composition comprises the sea water elements and minerals or sea water in an isotonic solution with a carbohydrate source. The composition preferably further includes dextrose and optionally, protein hydrolyzates, vitamins, and other nutritionally or pharmaceutically acceptable compositions. The composition is administered orally or parentally, in particular, intravenously or intramuscularly.