There is provided a method of manufacturing a heat exchanger, including a first step of mounting an end part of flat tube to a header, assembling the flat tube and fins, and sealing a part where the header and the end part is attached, and a second step of increasing an internal pressure of the flat tube to expand other part of flat tubes aside from the end parts with respect to the end part of the tube in order to make the fins and the other part of the flat tube in contact each other. According to this method of manufacturing, in the second step, the other part of the flat tube that passes through the fins is expanded, so that it is possible to mechanically join the flat tube and the fins, and a plate fin-type heat exchanger with high strength and heat exchange efficiency can be easily provided.