Briefly, values representative of ventricular end-diastolic volume (EDV)
are detected using ventricular electrodes and then heart failure, if
occurring within the patient, is evaluated based on ventricular EDV. In
this manner, ventricular EDV is used as a proxy for ventricular
end-diastolic pressure. By using ventricular EDV instead of ventricular
end-diastolic pressure, heart failure is detected and evaluated without
requiring sophisticated sensors or complex algorithms. Instead,
ventricular EDV is easily and reliably measured using impedance signals
sensed by implanted ventricular pacing/sensing electrodes. The severity
of heart failure is also evaluated based on ventricular EDV values and
heart failure progression is tracked based on changes, if any, in
ventricular EDV values over time.