A prosthetic component assembly, such as an acetabular cup, includes a shell, a bearing positioner and a bearing. The shell and bearing positioner are configured to facilitate orienting the bearing positioner in multiple orientations relative to the shell and for securing the bearing positioner in a selected orientation of the multiple orientations relative to the shell. The bearing is configured to be received in the bearing positioner at multiple rotational orientations for optimal joint biomechanics. The bearing positioner is selected from among a plurality of lateralized positioners to accommodate the joint anatomy.