The present invention is a system and a method for blood or urine sampling and sample-analysis, through a sampler that is a self blood-testing device or a urine-testing device. The system comprises a sampler, a transmission unit and an analysis unit. A patient may place a sampled blood drops on a sample strip and insert the strip into the sampler. The sampler may automatically prepare the sample and photograph it using a sample-preparation unit and a photography unit respectively. After the sample has been photographed, the resulting sample image may be transmitted to the analysis unit that may analyze the image through an image-processing algorithm. The analysis results may be automatically transmitted to the patient and to a medical authority, such as the patient's physician, a nurse, a clinic and the like, for further analysis, decision-making and treatment.