Complex comprising a peptide carrier of SEQ ID NO:1
GALFLGFLGAAGSTMGAWSQPKR.sub.1KRKVR.sub.2 and an appropriate siRNA,
wherein R.sub.1 represents any amino acid residue and more preferably K
or S, R.sub.2 is null or represents one of the following groups:
cysteamide, cysteine, thiol, amide, linear or ramified C.sub.1-C.sub.6
alkyl optionally substituted, primary or secondary amine, osidic
derivative, lipid, phospholipid or cholesterol and said siRNA is selected
to silence a target mRNA.