The present invention is a graphical user interface and method of operation for searching, and selecting items from, a database. The invention provides a convenient mechanism to thoroughly search a database for useful items. The invention runs in the background, dynamically annotating the active part of a main application's user interface with an indicator, to show a user of a main application that useful items may be available in a database. The trigger for initially activating the mechanism for searching and selecting in a main application is the same as the trigger for activating another round of searching the database, thus minimizing the diversion of a user's attention away from the main application. A user may select an item from the database for use in the main application. This might involve inserting a word into text with a word processor; the items may be words, and the database may be a thesaurus or dictionary, for example. Other examples are utilizing an image with a graphics application, or placing an order to buy an item with a purchasing application. One aspect of the present invention is a method for searching, and selecting items from, a database. Another aspect of the present invention is a system for executing the method of the present invention. A third aspect of the present invention is as a set of instructions on a computer-usable medium, or resident in a computer system, for executing the method of the present invention.