The invention provides low molecular compounds having activity which
inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3
antagonists. The invention also provides compounds represented by formula
(I) below, pharmaceutically acceptable acid adducts thereof, or
pharmaceutically acceptable C.sub.1-C.sub.6 alkyl adducts thereof, as
well as pharmaceutical compositions comprising them as effective
ingredients, which are useful for treatment or prevention of diseases
associated with CCR3, such as asthma and allergic rhinitis. ##STR00001##