Compounds of formula (I),
##STR00001##
or pharmaceutically acceptable derivatives thereof, wherein: R.sup.1
represents H, C.sub.1-6alkyl, C.sub.1-6alkyloxy, C.sub.3-8cycloalkyl, or
halo; R.sup.2 represents H, C.sub.1-6alkyl (optionally substituted by
R.sup.3), phenyl (optionally substituted by CN), or Het; R.sup.3
represents OH, CN, Het, --R.sup.4--C.sub.1-6alkyl, or CONR.sup.5R.sup.6;
R.sup.4 represents --CO.sub.2--, or --O--; R.sup.5 and R.sup.6
independently represent H, C.sub.1-6alkyl (optionally substituted by
OR.sup.7) or C.sub.3-8cycloalkyl; R.sup.7 represents H or
C.sub.1-6alkyl; Het represents a five or six membered aromatic
heterocyclic group containing (i) from one to four nitrogen heteroatom(s)
or (ii) one or two nitrogen heteroatom(s) and one oxygen or one sulphur
heteroatom or (iii) one or two oxygen or sulphur heteroatom(s), said
heterocyclic group being optionally substituted by one or more groups
selected from CN and C.sub.1-6alkyl; R.sup.8 represents
C.sub.1-6alkyl, C.sub.1-6alkyloxy, C.sub.3-8cycloalkyl, or halo; and
R.sup.9 and R.sup.10 independently represent H, C.sub.1-6alkyl,
C.sub.1-6alkyloxy, CN, CF.sub.3 or halo;may be useful for treating
endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis,
primary and secondary dysmenorrhoea (including symptoms of dyspareunia,
dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.