A porous .beta.-tricalcium phosphate material for bone implantation is
provided. The multiple pores in the porous TCP body are separate discrete
voids and are not interconnected. The pore size diameter is in the range
of 20-500 .mu.m, preferably 50-125 .mu.m. The porous .beta.-TCP material
provides a carrier matrix for bioactive agents and can form a moldable
putty composition upon the addition of a binder. Preferably, the
bioactive agent is encapsulated in a biodegradable agent. The invention
provides a kit and an implant device comprising the porous .beta.-TCP,
and a bioactive agent and a binder. The invention also provides an
implantable prosthetic device comprising a prosthetic implant having a
surface region, a porous .beta.-TCP material disposed on the surface
region and optionally comprising at least a bioactive agent or a binder.
Methods of producing the porous .beta.-TCP material and inducing bone
formation are also provided.