A cable or the like protection and guide device is disclosed and claimed. The shape of a shoe, which is mounted on the cable or the like protection and guide device, and a structure of a mounting portion on a cable or the like protection and guide device side, are simplified, the collision sound generated when shoes slide on each other is suppressed and the endurance of the shoe is improved whereby a long life is obtained. The above-mentioned problems are solved by a cable or the like protection and guide device, characterized in that a shoe is provided on the flexion inner circumferential side of each link plate, a front end portion and a rear end portion of the shoe and a side wall portion of the shoe having a hook, which engages with a concave portion provided on a side plate of the link plate are molded by a soft resin and a center portion of the shoe having a protrusion portion inserted into an insertion opening provided in a upper end surface of the link plate is molded by a hard resin, that is by use of a two-color molding process.