The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.

 
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< Polypeptide having heparanase activity

> Multivalent immunoglobulin-based bioactive assemblies

> Methods of reducing bone absorption comprising administering an antibody that binds OBM

~ 00515