An apparatus and related methods for facilitating surface-enhanced Raman spectroscopy (SERS) is described. The apparatus comprises a SERS-active structure near which a plurality of analyte molecules are disposed and an actuation device in actuable communication with the SERS-active structure to deform the SERS-active structure while the analyte molecules are disposed therenear. The deformation of the SERS-active structure varies an intensity of radiation Raman-scattered from the analyte molecules.