In a UMTS wireless communication system, the enhanced dedicated physical control channel (E-DPCCH) that is usually always transmitted together with the enhanced dedicated physical data channel (E-DPDCH) on the uplink from a UE to a NodeB is instead only transmitted when a predetermined "start criterion" is met and is turned off when a predetermined "stop criterion" is met until a "start criterion" is later met again. The UE starts transmitting E-DPCCH whenever the corresponding E-DPDCH transport format combination is different from the previous one in the same HARQ process or some other "start criterion" is met. Multiple mechanisms can be used to decide when the UE should switch off E-DPCCH transmission after the transport format combination of E-DPDCH has changed.