Acyloxyalkyl carbamate prodrugs of .alpha.-amino acids, pharmaceutical compositions thereof, methods of making acyloxyalkyl carbamate prodrugs of .alpha.-amino acids and methods of using acyloxyalkyl carbamate prodrugs of .alpha.-amino acids, and pharmaceutical compositions thereof to treat a disease are disclosed. Acyloxyalkyl carbamate prodrugs of .alpha.-amino acids suitable for oral administration using sustained release dosage forms are also disclosed.

 
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