A force feedback and interactive system is provided in the present invention, wherein the force feedback and interactive system utilizes a mechanism for detecting weight or center of gravity and reacted force from an operator on a multi-axis motion platform, and a main controller which is a kernel of data processing and motion simulating of the multi-axis motion platform. Besides having complete mathematical simulation model for calculating reaction force variation according to the received operating command, force status and weight of the operator and having algorithm for simulating the motion of multi-axis motion platform so as to calculate the motion and instantaneous position of the multi-axis motion platform in space, the system can also provide function of force feedback for enhancing the virtual reality while being applied in various Human-Machine Interaction simulating field.