The present invention relates to thieno[2,3-d]-pyrimidine compounds having
fungicidal activity. Specifically, the present invention relates to
compounds having the Formula (I): ##STR00001## wherein each R1, R2 and
R3 is independently selected from the group consisting of H, halogen, and
alkyl; A is selected from the group consisting of H and alkyl; W is
selected from the group consisting of NH and O; D is selected from O, NH
and S; E is (--C(O)--).sub.p--R', wherein p is 0 or 1 and R' is selected
from the group consisting of optionally substituted rings selected from
phenyl. furanyl, pyridinyl, pyridinyl-N-oxide, pyrimidinyl, pyridazinyl,
pyrazinyl, thiazolyl, triazinyl, thiadiazolyl, oxazolyl, isoxazolyl,
thienopyrimidinyl, and pyrimidine fused with an aromatic or
heteroaromatic ring selected from bejizene, oxazole, isoxazole, furan,
thiazole, pyrimidine, pyridine, pyrrole, pyrazine, and thionhene; each
ring being ontionally substituted with one or more substituents selected
from the group consisting of alkyl, alkenyl, alkynyl, halogen, haloalkyl,
alkoxy, haloalkoxy, nitro, cyano, alkylsulfonyl, alkylsulfoxide,
alkylthio, alkoxyiminoalkyl, alkylcarbonyl, alkoxycarbonyl,
aminocarbonyl, hydroxycarbonyl, phenyicarbonyl, forrnyl,
hydrazidocarbonyl, amidoamino, pyrazolyl, triazolonyl, oxadiazolyl,
phenyl, nyridinyl, and phenoxyalkyl; B is selected from the group
consisting of halogen, alkyl, haloalkyl, and haloalkoxy; n is an integer
from 0 to 3; and m is an integer from 0 to 4 with the proviso that when D
is O or S and E is phenyl, then E is not further substituted with
halogen.