Systems and methods for interference cancellation for high spectral efficiency satellite communications enabling efficient utilization of available bandwidth through overlapping adjacent channels. Data information is received along with noise information, and a filter bank is adapted to receive and filter the waveform and output channel information including a combination of data signals and adjacent channel interference signals. The filter bank is further adapted to provide estimated data signals and to calculate estimated interference signals. One or more interference generating processors are adapted to receive the calculated estimated interference signals to enable the interference generating processor to generate interference signals corresponding to the calculated estimated interference signals. The interference generating processor subtracts the interference signals from the estimated data signals in order to output relatively more accurate estimated data signals. A decision device is provided for use with the interference generating processors for estimating data signals in accordance with the relative ability of the interference processor to cancel interference with the estimated interference signals.