A printing apparatus, a printing system, and a prediction method of the usage of a printing agent can be configured to predict, prior to a processing for developing a printing image, the usage of a printing agent required for the printing. In order to do so, layout information is firstly analyzed prior to a processing for developing a printing image, thereby calculating an area in which object information arranged based on the layout information is printed. Then, based on the calculated printing area, the usage of the printing agent required for printing the object information is predicted.