A method for measuring and aligning wheels of a vehicle using a machine vision alignment apparatus including optical scanning devices and optically scannable targets. The method includes prompting a user of the alignment apparatus to choose between a standard alignment and a two-wheel alignment, conducting a standard alignment if the user chooses a standard alignment, prompting the user to choose between two targets or four targets if the user chooses a two-wheel alignment, conducting a two-wheel, two-target alignment procedure using the optical scanning devices if the user chooses two targets, and conducting a two-wheel, four-target alignment procedure using the optical scanning devices if the user chooses four targets.