Jinshuye styptic compositions, preparation methods and applications thereof are disclosed. A Jinshuye styptic composition is a plant preparation made by extracting leaf and stem of sweet potato (Ipomoea batatas, Jinshu), by purification and water extraction to obtain polysaccharides as active ingredients from the raw materials. Such a composition has the effects of invigorating spleen, cooling blood and stopping bleeding. Such a composition can be used for treatment of ITP, thrombocytopenia caused by radiotherapy and chemotherapy of tumors, and skin purpura caused by other factors.