The present invention discloses a polypeptide participating in pyridoxine biosynthesis, a polynucleotide coding the polypeptide and those uses. Particularly, this present invention discloses a polypeptide participating in pyridoxine biosynthesis, a polynucleotide coding the polypeptide, a method for inducing plant growth inhibition, a method for screening a compound inducing plant growth inhibition, and composition for inducing plant growth inhibition which comprises the compound obtained by the screening method.