A reporter system reflecting the transport process that transports
GPI-anchored proteins to the cell wall was constructed and compounds
inhibiting this process were discovered. Further, genes conferring
resistance to the above compounds were identified and methods of
screening for compounds that inhibit the activity of the proteins encoded
by these genes were developed. Therefore, through the novel compounds,
the present invention showed that antifungal agents having a novel
mechanism, i.e. inhibiting the process that transports GPI-anchored
proteins to the cell wall, could be achieved.