A medical inspection device. A housing includes a transparent plate. A circuit board is disposed in the housing. At least one light-emitting element is disposed on and electrically connected to the circuit board. The light-emitting element is opposite to the transparent plate. Light from the light-emitting element is output to the exterior of the housing through the transparent plate. An image sensor is disposed on and electrically connected to the circuit board. The image sensor is opposite to the transparent plate. An image in the exterior of the housing is received by the image sensor through the transparent plate and converted into an image signal thereby. A grip is detachably connected to the housing. A signal transmission line is detachably connected to the circuit board and fit in the grip and extends to the exterior of the grip, outputting the image signal.