The present invention provides glucopyranosyloxybenzylbenzene derivatives
represented by the general formula: ##STR00001## wherein P represents a
hydrogen atom or a group forming a prodrug; R.sup.1 represents a hydrogen
atom, an optionally substituted amino group, a carbamoyl group, an
optionally substituted lower alkyl group, an optionally substituted lower
alkoxy group, etc.; R.sup.2 represents a hydrogen atom or a lower alkyl
group; and R.sup.3 represents an optionally substituted lower alkyl
group, an optionally substituted lower alkoxy group, an optionally
substituted lower alkylthio group, etc., which have an improved oral
absorption, and exert an inhibitory activity in human SGLT2, and
therefore are useful as drugs for the prevention or treatment of a
disease associated with hyperglycemia such as diabetes, diabetic
complications or obesity, or pharmaceutically acceptable salts thereof,
and pharmaceutical uses thereof.