A pharmaceutical composition and a beverage composition comprising the
following three components (A), (B) and (C): (A) L-arginine or a salt
thereof; (B) caffeine or a salt thereof; and (C) at least one substance
selected from the group consisting of vitamin C or a derivative thereof,
vitamin E or a derivative thereof and folic acid or a derivative thereof.
The compositions show an effect of L-arginine even at a low L-arginine
content, and therefore can be suitably used for the prevention,
amelioration and/or treatment of at least one disease selected from the
group consisting of arteriosclerosis, angiectasia, hyperlipemia,
climacteric disorder, diabetes, angina pectoris, hypertension, erectile
dysfunction, thrombosis, immunodeficiency, dementia, gestosis,
respiratory failure and hemorrhoid, in the form of a pharmaceutical
preparation or a beverage.