An integrated detection system that includes a first threat detection apparatus and a second threat detection apparatus is provided. The first threat detection apparatus may identify one or more areas within an item of baggage that may contain threats. Example threats include, but are not limited to, explosives, weapons, illegal drugs, and hazardous matter, among others. The remaining areas are in theory deemed clear of threats. The second threat detection apparatus may be configured to inspect only the suspect areas of the item of baggage that was previously identified by the first threat detection apparatus. This improves throughput and lowers the false positive rate. A method for intelligently fusing the independent information obtained by the first and second threat detection apparatuses is also provided.